CO RADS grade of HRCT Thorax and RT PCR testing for the diagnosis of coronavirus disease 2019 (COVID 19): A descriptive hospital based study of asymptomatic planned surgery cases.

Background: The coronavirus disease 2019 (COVID-19) reporting and data system (CO-RADS) grade of high-resolution computed tomography (HRCT)-thorax scan investigation is an innovative tool for the diagnosis of COVID-19 patients. By this tool, majority of moderate-to-severe COVID-19 patients are screened to detect lung pathologies. Hardly any study has explored its use vis-a-vis reverse transcriptase-polymerase chain reaction (RT-PCR) in asymptomatic patients. Objectives: (1) The objective of the study is to assess the frequency COVID-19 patients among asymptomatic subjects who were admitted in the hospital for planned surgery, (2) estimate the sensitivity and specificity of CO-RADS grade of HRCT-thorax investigation for the diagnosis of COVID-19 patients where RT-PCR test was considered as "Gold Standard" test. Methodology: A descriptive retrospective study was conducted by studying the records in the case files of 150 patients who were admitted in the Department of General Surgery, Man Mohini Health Clinic, Murshidabad, West Bengal for minor surgical procedures between September 1 and December 31, 2020. Data were collected from hospital records. The CO-RADS grade of HRCT-thorax investigation and RT-PCR test were performed for the diagnosis of severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) virus. The MS-excel application was applied for data analysis. Results: The mean age of the participants was 42.58 ± 14.29 years. A total of 17 (11%) and 39 (26%) of the patients were diagnosed with COVID-19 by HRCT-thorax and RT-PCR test, respectively. The sensitivity and specificity of CO-RADS grade of HRCT-thorax investigation for diagnosis of COVID-19 patients were 43.58% and 100%, respectively. The positive and negative predictive values of CO-RADS grade of HRCT-thorax investigation were 100% and 83.45%, respectively. Conclusions: The frequency of asymptomatic patients with COVID-19 that was missed by HRCT thorax was high, compared to the gold standard RT-PCR, reflecting its low sensitivity and low negative predictive value in the diagnosis of SARS-CoV-2 virus infection. Hence, it is difficult to conclude in favor of HRCT thorax as first-line screening modality in all individuals.

Résumé Contexte: Le système de notification et de données sur la maladie à coronavirus 2019 (COVID 19) (CO RADS) la tomographie (HRCT)­exploration du thorax est un outil innovant pour le diagnostic des patients COVID 19. Par cet outil, la majorité des Les patients COVID 19 modérés à sévères sont dépistés pour détecter les pathologies pulmonaires. Pratiquement aucune étude n'a exploré son utilisation vis-à-vis réaction en chaîne par transcriptase polymérase (RT PCR) chez des patients asymptomatiques. Objectifs: (1) L'objectif de l'étude est d'évaluer la fréquence Patients COVID 19 parmi les sujets asymptomatiques qui ont été admis à l'hôpital pour une chirurgie planifiée, (2) estimer la sensibilité et la spécificité de grade CO-RADS de l'investigation HRCT-thorax pour le diagnostic des patients COVID-19 où le test RT-PCR a été considéré comme "Gold Standard" test. Méthodologie: Une étude rétrospective descriptive a été menée en étudiant les dossiers des dossiers de 150 patients admis dans le département de chirurgie générale, clinique de santé Man Mohini, Murshidabad, Bengale occidental pour des interventions chirurgicales mineures entre septembre 1 et 31 décembre 2020. Les données ont été recueillies à partir des dossiers hospitaliers. Le grade CO RADS de l'examen HRCT thorax et du test RT PCR était réalisée pour le diagnostic du virus du coronavirus 2 lié au syndrome respiratoire aigu sévère (SRAS CoV 2). L'application MS Excel a été appliquée pour l'analyse des données. Résultats: L'âge moyen des participants était de 42,58 ± 14,29 ans. Au total, 17 (11 %) et 39 (26 %) des patients ont été diagnostiqués avec COVID 19 par HRCT thorax et test RT PCR, respectivement. La sensibilité et la spécificité du grade CO-RADS de l'investigation HRCT-thorax pour le diagnostic des patients COVID-19 étaient de 43,58 % et 100 %, respectivement. Les valeurs prédictives positives et négatives du grade CO RADS de L'investigation HRCT-thorax était de 100 % et 83,45 %, respectivement. Conclusions: La fréquence des patients asymptomatiques atteints de COVID 19 qui manqué par HRCT thorax était élevé, par rapport à la RT-PCR de référence, reflétant sa faible sensibilité et sa faible valeur prédictive négative dans le diagnostic d'infection par le virus SARS CoV 2. Par conséquent, il est difficile de conclure en faveur de HRCT thorax comme modalité de dépistage de première ligne chez tous les individus. Mots-clés: personnes asymptomatiques, tomodensitométrie haute résolution - thorax, transcriptase inverse-réaction en chaîne par polymérase maladie à coronavirus 2019.

Knowledge, attitudes, and practices towards COVID-19 among hospital staff of West Bengal during COVID-19 outbreak: A hospital based cross sectional study

Background: COVID-19 disease is a highly contagious and totally unknown disease which is caused by SARS-CoV-2. This disease spread throughout the world irrespective of social, economical and political variation. Health care staff are the frontline COVID-19 worrier and their understanding of this disease is very important. Aims and Objective: The aim of this study was to assess the knowledge, attitudes and practices (KAP) towards COVID-19 disease among the healthcare staff of a tertiary care hospital of West Bengal. Materials and Methods: An analytic cross-sectional study was conducted at Murshidabad Medical College, Murshidabad from 25th April, 2020 to 2nd May, 2020. A total of 214 health care staff (83 nurses, 75 doctors, 20 para-medical staff, 24 administrative staff, and 12 sweepers) participated in this questionnaire based KAP study. The questionnaire was prepared according to the World Health Organization' on Corona virus disease (COVID-19) "advice for the public". The Systematic random sampling procedure was employed for data collection. The data was analysed using T-test, ANOVA, chi-square test and regression model. The informed consent was taken from each participant. Results: Female (62%) participants were more than male (38%) participants. Mean age of the participants was 27.03±7.63 years. About the half participants were unmarried (55%) and studied up to bachelor's degree (49%). The overall knowledge score found to be "medium level" with 77% reporting correct answers. The knowledge score was statistically different among age group, education level, marital status and occupational group of health care staff in this hospital by univariate analysis. The good attitudes and good practices were not related with knowledge score. The majority of the respondents (78%) had confidence on their attitude that "India can win the battle against COVID-19". Only 86% participants wore masks while going out in the lock-down period and 79% participants had not visited any crowded place. Only 18% participants used traditional home remedies for flu like symptoms. In multivariate analysis, doctors were found with better knowledge score and attitude towards COVID-19 than other healthcare staff in this hospital. Conclusion: The two preventive practice (social isolation and mask use) and optimistic attitude towards COVID-19 of health care staff were not totally depended on COVID-19 related knowledge score. However, knowledge score was depended on marital status, educational background, age, occupation and place of residence. Government should emphasize more on COVID-19 related health education and health promotion programme at community level. [ABSTRACT FROM AUTHOR] Copyright of Asian Journal of Medical Sciences is the property of Manipal Colleges of Medical Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)